Principal Investigator

  • Dr. Ann-Na Cho

    Dr. Ann-Na Cho

    Lecturer (equivalent to Assistant Professor)
    Sydney Horizon Fellow
    NHMRC Emerging Leadership Fellow

  • Education

    2020 Ph.D. Department of Biotechnology, Yonsei University, Seoul, South Korea (Advisor: Prof. Seung-Woo Cho)
    2013 B. S. Department of Biology, Yonsei University, Seoul, South Korea

    Awards and Prizes

    2024 MIT Technology Review, Innovators Under 35 (TR35) Asia Pacific

    2024 Australian Museum Eureka Finalist, Outstanding Early Career Researcher
    2021 BRIC Hanbitsa ‘People who brought honor to Korea’
    2019 Best organoid data award. 2nd Place. The 2nd Annual meeting of Korean organoid society
    2019 Best Research Award. BK21 PLUS Initiative for Biological Function & Systems Symposium
    2018 Best Poster award. The 1st International Annual Meeting of Korean Organoid Society
    2018 Best Research Award. BK21 PLUS Initiative for Biological Function & Systems Symposium
    2017 Best Poster award. Annual meeting of Korean Society of Industrial and Engineering Chemistry
    2017 Best Poster presentation award. Annual meeting of Korean Society for Stem Cell Research
    2016 Best Research Award. BK21 PLUS Initiative for Biological Function & Systems Symposium

  • I'm a stem cell engineer, bio-manufacturer and neuroscientist

    with a focus on developing human brain organoids - laboratory models that mimic human brain physiology.

    We are pioneering the development of a human brain micro-physiology system in vitro, combining brain organoids with innovative biomedical engineering tools, including 3D brain-mimetic biomaterials and organ-on-a-chip technologies.

    Our goal is to generate a humanized blood-brain-inflammatory model in a dish for personalized disease modeling and therapeutic screening. I lead a team that uses cutting-edge tissue engineering and stem cell biology to create complex human brain tissue, incorporating not only neural cells but also the vasculature and immune system. This advanced, humanized brain model will enable in-depth studies of the interactions between the brain, blood vessels, and the immune system, opening new avenues for understanding brain function and developing personalized treatments.

PhD Students

  • Summer Cao

    Research Interest: Human Brain Organoid-on-Chip, Neural Circuit, Schizophrenia Modelling

  • Yuwei Yan

    Research Interest: Human Brain Micro-physiological Platform for Virus Infection Modelling and Treatment Screening​

Master Students

  • Suchaya Chunlasen

    Research Interest: Human region-specifc brain organoids

Honor Students

  • Holly Ferstl

    Research Interest: Vascularised brain-on-chip, Childhood dementia

  • Joel Lummis

    Research Interest: Investigation of Plasma Treated Surface Biofunctionalization for Enhanced Human Neuronal Cell Maturation and Functionality

  • Julian Lui

    Research Interest: Mechanotransduction and Aging in humanised brain model

  • Paige Jackson

    Research Interest: Developing 3D Synthetic Matrix to Investigate Extracellular Matrix, Neuroinflammation Modelling

  • Antonia Law

    Research Interest: Neuroinflammatory system-on-chip

  • Sophie Heathcote

    Research Interest: In Vitro Retinal Organoid for Drug Repurposing

Internship

  • Juliana Silva Polo

    Research Interest: In vitro Retinal/Optical Model for Disease Modelling and Mechanism/Therapeutics Study

  • Ravi Wikramanayake

    Research Interest: Drug re-purposing using human organoids

  • Henry Howard

    Research Interest: Neurodegenerative disease, protein engineering, and materials science

  • Manpreet Jivin B.M.

    Research Interest: Bioinformatics, in silico modeling, organ-on-a-chip technology, and developing 3D matrix structures to study mechanotransduction