Principal Investigator

  • Dr. Ann-Na Cho

    Dr. Ann-Na Cho

    Lecturer (equivalent to Assistant Professor)

    Group Leader of hBMS Lab
    Sydney Horizon Fellow
    NHMRC Emerging Leadership Fellow

  • Education

    2020 Ph.D. Department of Biotechnology, Yonsei University, Seoul, South Korea (Advisor: Prof. Seung-Woo Cho)
    2013 B. S. Department of Biology, Yonsei University, Seoul, South Korea

    Awards and Prizes

    2024/2025 Finalist. Women of Colour in STEM Sister Awards, Innovator Award

    2025 Recipient. University of Sydney, Dean’s Award, Outstanding Research

    2024 Recipient. University of Sydney Vice-Chacellor Award, Early Career Research of the Year

    2024 Recipient. Member of the Year, Nano Institute

    2024 Finalist. Asian-Australian Leadership Award, Education & Sciecne & Medicine sector

    2024 Recipient. MIT Technology Review, Innovators Under 35 Asia Pacific

    2024 Finalist. 2024 Nano Pitch Health Award, Sydney Nano Institute

    2024 Finalist.  Australian Museum Eureka Prizes finalists on Outstanding Early Career Researcher

    2022 1st Prize. Light Microscopy Australia/Volume Imaging Australia Image Competition on Live Cell Category.

  • I'm a stem cell engineer, bio-manufacturer and neuroscientist

    with a focus on developing human brain organoids - laboratory models that mimic human brain physiology.

    We are pioneering the development of a human brain micro-physiology system in vitro, combining brain organoids with innovative biomedical engineering tools, including 3D brain-mimetic biomaterials and organ-on-a-chip technologies.

    Our goal is to generate a humanized blood-brain-inflammatory model in a dish for personalized disease modeling and therapeutic screening. I lead a team that uses cutting-edge tissue engineering and stem cell biology to create complex human brain tissue, incorporating not only neural cells but also the vasculature and immune system. This advanced, humanized brain model will enable in-depth studies of the interactions between the brain, blood vessels, and the immune system, opening new avenues for understanding brain function and developing personalized treatments.

PhD Students

  • Summer Cao

    Research Interest: Whole Brain Organogenesis, Neural Circuit, Schizophrenia Modelling

  • Shihui Chen

    Research Interest: Neurodegenerative disease, Blood-brain-barrier-on-chip, Neuroinflammation

  • Henry Howard

    Research Interest: Electrode-on-chip, Biobrain, Neurotech, Motor Neurone Disease

Master’s students

  • Suchaya Chunlasen

    Research Interest: Mechanotransduction, Synthetic scaffold for Brain organoids

  • Yuxin Tang

    Research Interest: Vascularised brain organoid, bio fabrication, tissue engineering

  • Marloes Thijs

    Research Interest: Organoid-on-chip, neuroinflammation, molecular and cellular processes

Honours students

  • Samuel Dawson Kelly

    Research Interest: Blood-brain-barrier, functional barrier for drug development

  • Joe Zhou

    Research Interest: Synthetic hydrogel and organogenesis, Organoid intelligence

  • Holly Horswill

    Research Interest: Physiologically-relevant blood-brain-barrier, multiple sclerosis

  • Ravi Wikramanayake

    Research Interest: Drug re-purposing, high-throughput human organoids and analysis

Internship & Dalyell scholars

  • Kevin Zou

    Research Interest: Drug & Nanomedicine screening, Organoid-on-chip, neuroinflammation mechanism (Dalyell scholar)

  • Jacky Tran

    Dalyell

  • Sophie Moulds

    Dalyell

  • Aiko Tan

    Research Interest: Novel analysis tools and high-throughput organoid assay